Illustration

Molecular modeling of peptide interaction with hydroxyl surface

Nadeem Ahmad Vellore & Dr. Robert A Latour

This image results from our modeling of a specific protein (theronine-rich peptide) interacting with a surface in a physiological solution. The peptide is rendered by mapping electrostatic potential surface energy with representative water molecules (red), sodium ions (yellow) and chloride ions (cyan).

Molecular modeling of peptide interaction with hydroxyl surface  by Nadeem Ahmad Vellore & Dr. Robert A Latour

Understanding protein interactions with surfaces is a challenge in the field of biomaterials. When an implant is placed in the body, proteins such as peptides adsorb on the implant surface, which affect implant function. We are modeling the interactions in order to predict the changes in protein behavior when a surface is introduced. Computational simulation of these systems could help bioengineers create surfaces that would control protein adsorption onto the surfaces of implants.

Funding sources for research represented by the image:
National Institutes of Health: NIH R01 EB006163-0131

Right arrow SEM Shish Kebab SEM Shish Kebab  by Stanley Sims
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